Research Interests: The Hinck lab uses structural and biophysical tools (NMR, X-ray crystallography, SPR, ITC, etc.) to study the signaling proteins and receptors of the TGF-β family. TGF-β plays important physiologic and pathogenic roles, being implicated in immune regulation, cell proliferation/differentiation, and cancer progression. My research aims to characterize a parasitic TGF-β mimic that binds to the type 1 and type 2 TGF-β receptors (TβRI and TβRII) by characterizing the structure of this mimic and analyzing its binding interfaces with TβRI and TβRII. I use a combination of biochemical techniques, NMR, and ITC/SPR experiments.
Education:
B.A. in Biophysics, University of Michigan, 2016
PhD Advisor: Dr. Andrew P. Hinck
Lab Address:
email: anm276 [at] pitt.edu
Publications:
