Research Interests:

The Smithgall lab is focused on studying the roles of Src family kinases in cancers and the accessory protein Nef in HIV infection and pathogenesis. My research is focused on Src family kinases which are key members of nearly all signalling pathways in the human body and are characterized by their regulatory SH3 and SH2 domains N-terminal of the kinase domain. I use a combination of biochemical methods such as surface plasmon resonance and kinase assays with X-ray crystallography to investigate the mechanism of small molecule regulators of specific Src family kinases.

 

 

 

 

 

Education:  

B.S. Biochemistry, Northeastern University, 2018

 


PhD Advisor:  Dr. Thomas E. Smithgall

Lab Address:

Bridgeside Point II Room 533

100 Technology Dr

Pittsburgh, PA 15219 

 

 

email:  ARS289 [at] pitt.edu


Publications: