Research Interests:

The Dahl group primarily interested in studying and understanding the mechanical properties of the nucleus and actin cytoskeleton. I primarily use confocal microscopy, to study biophysical characteristics of force mechanotransduction through particle tracking, immunofluorescence, and FRET tension-sensor measurements. Cellular forces have been identified to play critical roles in the cell life cycle, but how the cell interprets and propagates mechanical perturbation is largely unknown. We endeavor to develop a better understanding of how force plays pivotal roles in determining cell fate.

 

 

Education:

BS Biophysics, Loyola University Chicago, December 2014


PhD Advisor:  Kris Noel Dahl

Lab Address: 

Doherty hall
5000 Forbes Ave
Pittsburgh PA 15213

 

email:  

Klavreny@andrew.cmu.edu

Kil23@pitt.edu

 


Publications:

  • Piperazine Derivatives Enhance Epithelial Cell Monolayer Permeability by Increased Cell Force Generation and Loss of Cadherin Structures, Shiyuan Zheng, Kirill Lavrenyuk, Nicholas G. Lamson, Katherine C. Fein, Kathryn A. Whitehead, and Kris Noel Dahl, ACS Biomaterials Science & Engineering 2020 6 (1), 367-374 , DOI: 10.1021/acsbiomaterials.9b01660