“Merkel Cell Polyomavirus Encodes Circular RNAs (circRNAs) Enabling a Dynamic circRNA/microRNA/mRNA Regulatory Network”
Bizunesh Abere, Hongzhao Zhou, Jinghui Li, Simon Cao, Tuna Toptan, Adam Grundhoff, Nicole Fischer, Patrick S. Moore, Yuan Chang
mBio Dec 2020, 11 (6) e03059-20; DOI: 10.1128/mBio.03059-20
Merkel cell polyomavirus makes a circular RNA as part of a feedback network controlling its own replication by targeting an inhibitory viral miRNA.
Detection of MCV circMCV-T BSJ (red) and early region T antigen transcripts by BaseScope in situ hybridization.